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The Fourth q-bio Summer School on Cellular Information Processing
The Fourth q-bio Summer School is sponsored by the New Mexico Center for Systems Biology, the Center for Nonlinear Studies at Los Alamos National Laboratory, and the Los Alamos Institute for Advanced Studies. Participants will attend daily lectures about theory and modeling of cellular regulatory systems and networks. They will work in small teams on open-ended projects under the guidance of the summer school faculty. The summer school is designed for graduate students, postdocs, or anyone with a quantitative background who is new to modeling cellular regulatory systems and networks. After the summer school, students will participate in the Fourth q-bio Conference in Santa Fe, NM, August 10-14, 2010. Summer School applications are due on February 26th, 2010 and can be found at http://cnls.lanl.gov/q-bio/summer_school.html.
The q-bio Summer School is not affiliated with arXiv.q-bio.
Contents
Logistics
School Themes
- Spatiotemporal modeling of cellular regulatory systems
- Stochastic biochemistry
- Multiscale modeling of biomolecules
- Other topics
Quote
“If I was a senior in college or a first-year graduate student trying to figure out what area to work in, I would be a computational biologist.” - Francis Collins (Director, National Institutes of Health)
Participants
Schedule Overview
Unless otherwise noted, the school schedule will consist of approximately 3 hours of lectures in the morning. A typical schedule will look like
- 9:00-10:45 -- Lecture One
- 10:45-11:00 -- Break
- 11:00-12:45 -- Lecture Two
Afternoons will be left for other activities, such as ad hoc lectures, student talks (please come prepared to give an informal talk about your research), discussions, and study sessions, work on homework projects, continuation of the participants' regular academic work, and recreation. A classroom with wireless internet access will be reserved for the school participants for all afternoons during the school program. Additionally, we expect the students to spend some of the afternoons with the school faculty, most of whom are scientists at LANL, familiarizing themselves with the workings of the research institution and potentially starting collaborative research with the faculty.
Detailed schedule
- July 25 - Sunday
- Arrive in Los Alamos
Week 1
- July 26 - Monday
- Opening remarks - 8:00 AM
- Lecture 1, Ruy Ribeiro, Dynamics of CD4+ T cells in HIV-1 infection
- Lecture 2, Brian Munsky, Stochastic effects in systems biology: theoretical foundations and experimental results (part 1) Slides--Part1
- Lunch discussion with lecturers
- Student Talk 1 - Christoph Zimmer
- July 27 - Tuesday
- Lecture 3, S. 'Gnana' Gnanakaran, How multiscale modeling approaches have been applied to study a wide variety of biological problems
- Lecture 4, William S. Hlavacek, Rule-based modeling (slides)
- Lunch discussion with lecturers
- Student Talk 2 - Erin Rivera
- 14:00-15:00, Jasmin Fisher, Microsoft Research Cambridge -- q-bio seminar talk.
- Student Talk 3 - Kentaro Hayashi
- Student Talk 4 - Abhinav Tiwari
- July 28 - Wednesday
- Lecture 5, Tanmoy Bhattacharya, Phylogenetics (slides)
- Lecture 6, Brian Munsky, Stochastic effects in systems biology: theoretical foundations and experimental results (part 2) Slides--Part2
- Lunch discussion with lecturers
- Student Talk 5 - Anat Burger
- Student Talk 6 - Erwin Schoof
- Student Talk 7 - Paolo Cazzaniga
- Student Talk 8 - Dario Pescini
- July 29 - Thursday
- Lecture 7, Alan S. Perelson, How to model a viral infection
- Lecture 8, Bridget S. Wilson, Protein clustering
- Lunch discussion with lecturers
- Student Talk 9 - Sam Schwartz
- Student Talk 10 - Duncan Wadsworth
- Student Talk 11 - Jean Hausser
- Student Talk 12 - Jiankui He
- July 30 - Friday
- Lecture 9, Bette Korber, HIV vaccine design
- Lecture 10, Anurag Sethi, Molecular dynamics and network theory approaches with special emphasis on signaling and intrinsically disordered proteins
- Lunch discussion with lecturers
- Student Talk 13 - Michael Nip
- Student Talk 14 - Michael de Freitas
- Student Talk 15 - Julio Belmonte
- Student Talk 16 - Maria Mateescu
- July 31 and August 1 (Saturday and Sunday)
- Ideas for weekend activities -- TBA
Week 2
- August 2 - Monday
- Lecture 11, Cynthia Reichhardt, Computational Modeling of Directed Motion in Self-Driven Systems such as Bacteria and Cells
- Lecture 12, Helen Wearing, University of New Mexico
- Lunch discussion with lecturers
- Guest Lecture - Ramit Mehr (slides)
- Student Talk 17 - Alvin Tamsir
- Student Talk 18 - Barak Peleg
- August 3 - Tuesday
- Lecture 13a, Arjun Raj, Measuring cell-to-cell variability with fluorescence microscopy and single molecule Fluorescence In Situ Hybridization (FISH) techniques.
- Lecture 13b, Babs Marrone, Measuring cell-to-cell variability with flow cytometry and fluorescence activated cell sorting. (slides)
- Lecture 14, Thomas Leitner, Molecular evolution: tracing HIV epidemics and the origin of the domestic dog
- Lunch discussion with lecturers
- Student Talk 22 - Rosemary Braun
- Student Talk 23 - Antoine Delmotte
- 14:00-15:00, Arjun Raj, University of Pennsylvania -- q-bio seminar talk A single molecule view of cell fate: FISHing for worm guts
- August 4 - Wednesday
- Lecture 15, Partha Ramakrishnan, Quantum mechanical and molecular modeling approaches with special emphasis on molecular recognition during host-pathogen and nanomaterial-protein Interactions
- Lecture 16A, Jim Werner, Fluorescence Correlation Spectroscopy (FCS) and 3 Dimensional Molecule Tracking:
- Lecture 16B, Brian Munsky, Using single-cell variability data (FISH and Flow Cytometry) to identify parameters and mechanisms of gene regulatory systems.
- Lunch discussion with lecturers
- Lecture 17, Arthur D. Lander, Biological Pattern and Growth: Mechanism and Control
- Student Talk 24 - Xiaojing Yang
- Student Talk 25 - Chunbo Lou
- August 5 - Thursday
- Lecture 18, Ryan Gutenkunst, Inferring population history and natural selection from genomic data
- Lecture 19, Giovanni Bellesia, Coarse-grained and statistical mechanical approaches with special emphasis on biofuels and membrane physics
- Lunch discussion with lecturers
- "Guest Lecture" - Ramit Mehr
- Student Talk 26 - Eyal Ben Isaac
- Special Talk - Mac Hyman, Tulane/Los Alamos, Good choices for great careers (this talk will start at 4 PM) (slides)
- August 6 - Friday
- Lecture 20, Ilya Nemenman, Signal processing in biochemical networks, Part 1.
- Lecture 21, Ilya Nemenman, Signal processing in biochemical networks, Part 2.
- Lunch discussion with lecturers
- Student Talk 27 - Paul Bogdan
- Student Talk 28 - Arfu Guo
- Student Talk 29 - Jonghyeon Shin
- Student Talk 30 - Sheng Wu
- August 7 and 8 (Saturday and Sunday)
- Ideas for weekend activities -- TBA
Week 3
- August 9 - Monday
- Lecture 22, Anton Zilman, History of Stochastic Modeling in Physics.
- Lecture 23, Anton Zilman, Advanced stochastic analyses: Fokker Planck equation, Moment Generating Functions, etc...
- Lunch - Panel discussion on the Necessary Complexity of Biological Models: Tanmoy Bhattacharya, Gnanakaran, S, Byron Goldstein, Ryan Gutenkunst, Ilya Nemenman
- Lecture 24, Elaine L. Bearer, Cellular dynamics: inside and outside
- Student Talk 34 - Mario Paz
- Student Talk 35 - Kimberly Kanigel-Winner
- August 10 - Tuesday
- Lecture 25, James R. Faeder, University of Pittsburgh School of Medicine
- Lecture 26,
Christopher A. Voigt, CANCELLED - Replacement 1/2 talk to be given by Alvin Tamsir. Synthetic biology - Lunch discussion with lecturers
- 14:00-15:00, Chris Bystroff, Rensselaer Polytechnic Institute -- q-bio seminar talk (this talk will take place in Room 203A/B of the Los Alamos Research Park building)
- Lecture 27, Tomasz Lipniacki, Polish Academy of Sciences
- August 11 - Wednesday
- Depart to Santa Fe for the q-bio Conference -- Students will take a NM Park & Ride bus to Santa Fe in the morning ($3 exact change is required); organizers will arrange for separate transport of luggage to the conference site. A van will be waiting with an organizer at the school hotel at 8:15 am for transport of luggage to the site of the conference.