Information processing by gradient sensing system: convergence of methods, divergence of means

Andre Levchenko (JHU)

Abstract

A variety of eukaryotic cells can sense gradients of extracellular chemical cues and follow the gradients in the processes of chemotaxis and chemotropism. How this sophisticated behavior is controlled and regulated and whether the underlying biochemical mechanisms are conserved across species and cell types are still open questions. In this talk, I will discuss the ongoing studies in our lab of several types of gradient sensing systems, including budding yeast and Xenopus spinal neurons, contrasting their information processing and decision making mechanisms.

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