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Fly Magnetism: Planar cell polarity in the wing
From Q-bio
Yoram Burak and Boris Shraiman
- Abstract
- We propose a model for the formation of planar cell polarity in the Drosophila wing, based on the hypotheses that the two membrane proteins Frizzled and Van-Gogh form complexes across inter-cellular interfaces. We analyze the dynamics of cell polarity taking into account the stochastic nature of underlying reactions, make quantitative predictions for polarity amplitude and orientation and explore their experimental implications.
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