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Stochastic effects in systems biology: theoretical foundations and experimental results (part 1)

From Q-bio

Topics

  • Introduction to Stochasticity and the Master Equation.
  • The importance of stochasticity in gene regulatory networks.
  • Discussion of a couple key examples.
  • The physics behind stochastic chemical kinetics.
  • Connection between deterministic reaction rates and propensity functions.
  • Derivation of the Master Equation for discrete stochastic processes.
  • Analysis of the master equation for a simple transcription process.
  • Discussion of the importance of stochasticity in small populations.

Slides

The introduction slides are available at: File:Munsky Intro.pdf

The first half of the slides are at: File:Munsky Part 1.pdf

The second half are available at: File:Munsky Part 2.pdf